Patients participating in the TRIDENT trial wear the Optune® System continuously for an average of at least 18 hours a day, but may take breaks during daily use for some activities. The treating physician might modify the treatment schedule and use of the device as needed.

Novocure will provide device support to patients and caregivers. 

Please note: While Novocure provides comprehensive technical support Optune, direct all medical questions to your trial clinician.

Using the Optune System

The Optune system is intended for continuous use for at least 18 hours a day. Optune does not interfere with household or personal electrical devices. There is no exposure of TTFields to non-users, such as co-workers and family members.

What does it look like?

Optune is a wearable, portable device. Use of Optune requires shaving of the scalp and the application of four adhesive patches called “transducer arrays” to the head. Naturally, some patients may be concerned about their appearance or their lifestyle while using the system. Patients can cover Optune by wearing head coverings, with a loose-weave wig, headscarf, or loose-fitting hat that allows airflow. The medical team will provide personalized assistance specific to each patient for wearing the device comfortably.

In addition to regularly shaving their head, patients will regularly change their arrays to ensure continuous treatment. Your medical team will assist in creating a plan and instructing you on array placement.

In addition to head coverings, the wires connecting the transducer arrays to the device can be concealed underneath the patient’s clothes. By doing so, the bag carrying the system may be the only element of the Optune system visible to others.


The device is designed to allow patients to maintain their lifestyle without interference to their daily routines such as walking outdoors, shopping, and meeting friends and family. Consult the treating physician ahead of time regarding any activity in question. In addition, Novocure can provide information to address lifestyle concerns.

The system’s bag can be worn as a backpack, a shoulder or a side (cross-body) bag. The total weight of the system, including a battery, is around 1.3 kilograms, or 2.7 pounds. Novocure can provide as many portable batteries as needed for patients who maintain an active lifestyle, which includes outdoor activities.

In order to ensure continuous treatment, patients will plug the Optune system in to an AC adapter when staying in a location for more than a few hours.