Patients participating in the PANOVA trial wear the system continuously but can take breaks during their daily use of the system, as long as the average time on TTFields throughout the entire treatment period is kept at 18 hours per day. The treating physician might modify the treatment schedule and use of the device as needed.

Novocure provides the patients with around the clock technical support through a local Device Support Specialist (DSS). While the DSS provides a comprehensive technical support, the medical team continues to address any medical questions and to make all treatment decisions together with the patient.

The use of the NovoTTF-100L(P) System involves the continuous operation of a medical device, which may be placed or carried inside a bag provided with the device. The system’s bag blends well with mainstream bag trends and can be used as a backpack, a shoulder or a side (cross-body) bag. The transducer arrays placed around the abdominal region can be completely covered by standard clothing and become invisible to others. Therefore, the system is completely concealed during the activation of the treatment, aside from the part that connects the arrays to the device itself.

The NovoTTF-100L(P) System was carefully designed to allow patients to maintain their lifestyle without interference to their daily routines, such as walking outdoors, shopping, and meeting friends and family. The treating physician can be consulted ahead of time regarding any activity in question. In addition, the local DSS can provide information for lifestyle concerns.

Novocure can provide as many portable batteries as needed for patients who maintain active lifestyle, whichcan include outdoor activity.

While the total weight of the system including a battery is around 3 kilograms, the vast majority of patients are not expected to be physically carrying the system most of their time, but will rather use it for different intervals while it is continuously placed in one location (e.g. on a desk, a table or on the floor inside the carrying bag).

The use of the device will not interfere with household or standard personal electrical devices. There is no exposure of TTFields to non-users, such as co-workers and family members.